Mining Small Routine Clinical Data: A Population Pharmacokinetic Model and Optimal Sampling Times of Capecitabine and its Metabolites

Purpose: The present study was performed to demonstrate that small amounts of routine clinical data allow to generate valuable knowledge. Concretely, the aims of this research were to build a joint population pharmacokinetic model for capecitabine and three of its metabolites (5-DFUR, 5-FU and 5-FUH...

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Bibliographic Details
Main Authors: Oyaga-Iriarte, E. (Esther), Insausti, A. (Asier), Bueno, L. (Lorea), Sayar, O. (Onintza), Aldaz, A. (Azucena)
Format: info:eu-repo/semantics/article
Language:eng
Published: University of Alberta Libraries 2021
Subjects:
Online Access:https://hdl.handle.net/10171/61900