Prediction of irinotecan toxicity in metastatic colorectal cancer patients based on machine learning models with pharmacokinetic parameters

Irinotecan (CPT-11) is a drug used against a wide variety of tumors, which can cause severe toxicity, possibly leading to the delay or suspension of the cycle, with the consequent impact on the prognosis of survival. The main goal of this work is to predict the toxicities derived from CPT-11 using a...

Full description

Bibliographic Details
Main Authors: Oyaga-Iriarte, E. (Esther), Insausti, A. (Asier), Sayar, O. (Onintza), Aldaz, A. (Azucena)
Format: info:eu-repo/semantics/article
Language:eng
Published: Elsevier BV 2021
Subjects:
Online Access:https://hdl.handle.net/10171/61901