A permeability-increasing drug synergizes with bacterial efux pump inhibitors and restores susceptibility to antibiotics in multi-drug resistant Pseudomonas aeruginosa strains

A permeability-increasing drug synergizes with bacterial efux pump inhibitors and restores susceptibility to antibiotics in multi-drug resistant Pseudomonas aeruginosa strains

Resistance to antibiotics poses a major global threat according to the World Health Organization. Restoring the activity of existing drugs is an attractive alternative to address this challenge. One of the most efficient mechanisms of bacterial resistance involves the expression of efflux pump syste...

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Bibliographic Details
Main Authors: Raquel, Shahrour, H. (Hawraa), Pitts, B. (Betsey), Stewart, P.S. (Philip S.), Sánchez-Gómez, S. (Susana), Martinez-de-Tejada, G. (Guillermo)
Format: info:eu-repo/semantics/article
Language:eng
Published: Springer Science and Business Media LLC 2021
Subjects:
Materias Investigacion::Ciencias de la Salud::Microbiología y biología molecular
Online Access:https://hdl.handle.net/10171/62141

Internet

https://hdl.handle.net/10171/62141

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