Primaquine–quinoxaline 1,4‑di‑N‑oxide hybrids with action on the exo‑erythrocytic forms of Plasmodium induce their efect by the production of reactive oxygen species

Background: The challenge in anti-malarial chemotherapy is based on the emergence of resistance to drugs and the search for medicines against all stages of the life cycle of Plasmodium spp. as a therapeutic target. Nowadays, many molecules with anti-malarial activity are reported. However, few stu...

Full description

Bibliographic Details
Main Authors: Bonilla‑Ramírez, L. (Leonardo), Galiano, S. (Silvia), Quiliano, M. (Miguel), Aldana, I. (Ignacio), Pabon, A. (Adriana)
Format: info:eu-repo/semantics/article
Language:eng
Published: Springer Science and Business Media LLC 2022
Subjects:
Online Access:https://hdl.handle.net/10171/63629