Potential of sulfur-selenium isosteric replacement as a strategy for the development of new anti-chagasic drugs

Current treatment for Chagas disease is based on only two drugs: benznidazole and nifurtimox. Compounds containing sulfur (S) in their structure have shown promising results in vitro and in vivo against Trypanosoma cruzi, the parasite causing Chagas disease. Notably, some reports show that the isost...

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Bibliographic Details
Main Authors: Rubio-Hernández, M. (Mercedes), Alcolea-Devesa, V. (Verónica), Pérez-Silanes, S. (Silvia)
Format: info:eu-repo/semantics/article
Language:eng
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10171/63644