Examination of multiple Trypanosoma cruzi targets in a new drug discovery approach for Chagas disease

Examination of multiple Trypanosoma cruzi targets in a new drug discovery approach for Chagas disease

Chagas disease (CD) is a centenarian neglected parasitosis caused by the protozoan Trypanosoma cruzi (T. cruzi). Despite the continuous efforts of many organizations and institutions, CD is still an important human health problem worldwide. A lack of a safe and affordable treatment has led drug disc...

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Bibliographic Details
Main Authors: Beltrán-Hortelano, I. (Iván), Alcolea-Devesa, V. (Verónica), Font, M. (María), Pérez-Silanes, S. (Silvia)
Format: info:eu-repo/semantics/article
Language:eng
Published: Elsevier 2022
Subjects:
Trypanosoma cruzi
Triosephosphate isomerase
Sterol 14α-demethylase
CYP51
Dihydroorotate dehydrogenase
Cruzain
Trypanothione reductase
Superoxide dismutase
Pteridine reductase
Dihydrofolate reductase
Thymidylate synthase
Online Access:https://hdl.handle.net/10171/63734

Internet

https://hdl.handle.net/10171/63734

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