Egg consumption and dyslipidemia in a Mediterranean cohort
Introduction and objectives: Our aim was to prospectively evaluate the association between egg consumption and dyslipidemia in a Mediterranean cohort. Methods: We followed-up 13,104 Spanish university graduates for a mean period of 8 years. Dietary habits at baseline were assessed using a validate...
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| Format: | info:eu-repo/semantics/article |
| Language: | eng |
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Aran
2022
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| Online Access: | https://hdl.handle.net/10171/64383 |
| _version_ | 1793400021126742016 |
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| author | Vazquez-Ruiz, Z. (Zenaida) Fuente-Arrillaga, C. (Carmen) de la Bes-Rastrollo, M. (Maira) Zazpe, I. (Itziar) Santiago, S. (Susana) Razquin, C. (Cristina) Toledo, E. (Estefanía) Martinez-Gonzalez, M.A. (Miguel Ángel) |
| author_facet | Vazquez-Ruiz, Z. (Zenaida) Fuente-Arrillaga, C. (Carmen) de la Bes-Rastrollo, M. (Maira) Zazpe, I. (Itziar) Santiago, S. (Susana) Razquin, C. (Cristina) Toledo, E. (Estefanía) Martinez-Gonzalez, M.A. (Miguel Ángel) |
| author_sort | Vazquez-Ruiz, Z. (Zenaida) |
| collection | DSpace |
| description | Introduction and objectives: Our aim was to prospectively evaluate the association between egg consumption and dyslipidemia in a Mediterranean cohort.
Methods: We followed-up 13,104 Spanish university graduates for a mean period of 8 years. Dietary habits at baseline were assessed using
a validated semi-quantitative 136-item food-frequency questionnaire. Self-reported blood concentrations of total cholesterol, high-density lipoproteins cholesterol (HDL-c) and triglycerides were evaluated according to categories of egg consumption after 6 and 8 years of follow-up. We
also assessed the association between baseline egg consumption and the incidence of hypercholesterolemia, low HDL-c concentrations and
hypertriglyceridemia during follow-up.
Results: We observed a significant inverse association for intermediate levels of egg consumption (2 to 4 eggs/week vs. less than 1 egg/week)
and hypertriglyceridemia with OR = 0.71 (95% confidence interval [CI]: 0.54 to 0.93, p < 0.05) in the multivariable-adjusted model. Using HDL-c
values after 8-year follow-up, we found an association between higher egg consumption and lower HDL-c levels (p for trend = 0.02) with an
adjusted difference of –4.01 mg/dl (-7.42 to -0.61) for > 4 vs. < 1 egg/week. Lower means of triglycerides were found in each of the three
upper categories of egg consumption compared to the lowest category (< 1 egg/week) with significant results for some of these categories both
after 6 and 8 year follow-up.
Conclusions: Our data do not support that higher egg consumption was associated with abnormal blood levels of total cholesterol or triglycerides;
an inverse association with HDL-c as a quantitative variable was found only in one of our analyses. |
| format | info:eu-repo/semantics/article |
| id | oai:dadun.unav.edu:10171-64383 |
| institution | Universidad de Navarra |
| language | eng |
| publishDate | 2022 |
| publisher | Aran |
| record_format | dspace |
| spelling | oai:dadun.unav.edu:10171-643832022-10-07T01:06:53Z Egg consumption and dyslipidemia in a Mediterranean cohort Vazquez-Ruiz, Z. (Zenaida) Fuente-Arrillaga, C. (Carmen) de la Bes-Rastrollo, M. (Maira) Zazpe, I. (Itziar) Santiago, S. (Susana) Razquin, C. (Cristina) Toledo, E. (Estefanía) Martinez-Gonzalez, M.A. (Miguel Ángel) Egg consumption Cohort Cholesterol HDL-c Triglycerides Dyslipidemia Consumo de huevo Cohorte HDL-c Triglicéridos Dislipidemia Colesterol Introduction and objectives: Our aim was to prospectively evaluate the association between egg consumption and dyslipidemia in a Mediterranean cohort. Methods: We followed-up 13,104 Spanish university graduates for a mean period of 8 years. Dietary habits at baseline were assessed using a validated semi-quantitative 136-item food-frequency questionnaire. Self-reported blood concentrations of total cholesterol, high-density lipoproteins cholesterol (HDL-c) and triglycerides were evaluated according to categories of egg consumption after 6 and 8 years of follow-up. We also assessed the association between baseline egg consumption and the incidence of hypercholesterolemia, low HDL-c concentrations and hypertriglyceridemia during follow-up. Results: We observed a significant inverse association for intermediate levels of egg consumption (2 to 4 eggs/week vs. less than 1 egg/week) and hypertriglyceridemia with OR = 0.71 (95% confidence interval [CI]: 0.54 to 0.93, p < 0.05) in the multivariable-adjusted model. Using HDL-c values after 8-year follow-up, we found an association between higher egg consumption and lower HDL-c levels (p for trend = 0.02) with an adjusted difference of –4.01 mg/dl (-7.42 to -0.61) for > 4 vs. < 1 egg/week. Lower means of triglycerides were found in each of the three upper categories of egg consumption compared to the lowest category (< 1 egg/week) with significant results for some of these categories both after 6 and 8 year follow-up. Conclusions: Our data do not support that higher egg consumption was associated with abnormal blood levels of total cholesterol or triglycerides; an inverse association with HDL-c as a quantitative variable was found only in one of our analyses. Introducción y objetivos: evaluar prospectivamente la asociación entre el consumo de huevo y el riesgo de dislipidemia en una cohorte mediterránea. Métodos: se siguieron 13.104 graduados universitarios españoles durante un periodo medio de 8 años. La dieta se evaluó al inicio utilizando un cuestionario semicuantitativo de frecuencia de consumo de alimentos repetidamente validado. Las concentraciones sanguíneas de colesterol total, lipoproteínas de alta densidad (HDL-c) y triglicéridos autorreferidas fueron evaluadas según categorías de consumo de huevo tras 6 y 8 años de seguimiento. También se evaluó la asociación entre el consumo basal de huevo y la incidencia de hipercolesterolemia, concentraciones bajas de HDL-c e hipertrigliceridemia durante el seguimiento. Resultados: se observó una asociación entre los niveles intermedios de consumo de huevo (2-4 unidades/semana frente a < 1 unidad/semana) y menor riesgo de hipertrigliceridemia con OR = 0,71 (intervalo de confianza del 95% [IC]: 0,54 a 0,93, p < 0,05) en el modelo más ajustado. Tras 8 años de seguimiento, encontramos una asociación entre un mayor consumo de huevo y menores niveles de HDL-c (p tendencia lineal = 0,02) con una diferencia ajustada de -4,01 mg/dl (-7,42 a -0,61) para > 4 vs. < 1 unidad/semana. Se encontraron menores concentraciones de triglicéridos en las tres categorías superiores de consumo de huevo en comparación con la inferior con resultados significativos para algunas de estas categorías después de 6 y 8 años de seguimiento. Conclusiones: un mayor consumo de huevo no se asoció con niveles anormales de colesterol total o triglicéridos; se encontró una asociación inversa con HDL-c como variable cuantitativa solo en uno de nuestros análisis. 2022-10-06T07:56:11Z 2022-10-06T07:56:11Z 2018 info:eu-repo/semantics/article https://hdl.handle.net/10171/64383 eng info:eu-repo/semantics/openAccess application/pdf Aran |
| spellingShingle | Egg consumption Cohort Cholesterol HDL-c Triglycerides Dyslipidemia Consumo de huevo Cohorte HDL-c Triglicéridos Dislipidemia Colesterol Vazquez-Ruiz, Z. (Zenaida) Fuente-Arrillaga, C. (Carmen) de la Bes-Rastrollo, M. (Maira) Zazpe, I. (Itziar) Santiago, S. (Susana) Razquin, C. (Cristina) Toledo, E. (Estefanía) Martinez-Gonzalez, M.A. (Miguel Ángel) Egg consumption and dyslipidemia in a Mediterranean cohort |
| title | Egg consumption and dyslipidemia in a Mediterranean cohort |
| title_full | Egg consumption and dyslipidemia in a Mediterranean cohort |
| title_fullStr | Egg consumption and dyslipidemia in a Mediterranean cohort |
| title_full_unstemmed | Egg consumption and dyslipidemia in a Mediterranean cohort |
| title_short | Egg consumption and dyslipidemia in a Mediterranean cohort |
| title_sort | egg consumption and dyslipidemia in a mediterranean cohort |
| topic | Egg consumption Cohort Cholesterol HDL-c Triglycerides Dyslipidemia Consumo de huevo Cohorte HDL-c Triglicéridos Dislipidemia Colesterol |
| url | https://hdl.handle.net/10171/64383 |
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