Oncolytic adenovirus Delta-24- RGD engineered to express 4-1BBL or OX40L as therapeutic approach for diffuse intrinsic pontine gliomas

Oncolytic adenovirus Delta-24- RGD engineered to express 4-1BBL or OX40L as therapeutic approach for diffuse intrinsic pontine gliomas

Pediatric tumors appear during childhood and adolescence and are diagnosed from 0 to 19 years old.1 The WHO estimates that 400,000 cases are diagnosed every year globally, which account for about 1% of all cancer diagnoses. 2 Pediatric tumors differ substantially from tumors occurring in adults....

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Bibliographic Details
Main Authors: Laspidea, V. (Virginia), Alonso-Roldán, M.M. (Marta María), Patiño-García, A. (Ana)
Format: info:eu-repo/semantics/doctoralThesis
Language:eng
Published: Universidad de Navarra 2023
Subjects:
Materias Investigacion::Ciencias de la Salud::Oncología
Pediatric brain tumors
Oncolytic virotherapy
T regulatory cells
Treg
Delta-24-ACT
Delta-24-RGDOX
Intrinsic pontine gliomas
Online Access:https://hdl.handle.net/10171/65228

Internet

https://hdl.handle.net/10171/65228

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