Modulation of Haemophilus influenzae interaction with hydrophobic molecules by the VacJ/MlaA lipoprotein impacts strongly on its interplay with the airways

Modulation of Haemophilus influenzae interaction with hydrophobic molecules by the VacJ/MlaA lipoprotein impacts strongly on its interplay with the airways

Airway infection by nontypeable Haemophilus influenzae (NTHi) associates to chronic obstructive pulmonary disease (COPD) exacerbation and asthma neutrophilic airway inflammation. Lipids are key inflammatory mediators in these disease conditions and consequently, NTHi may encounter free fatty acids d...

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Main Authors: Fernández-Calvet, A. (Ariadna), Rodríguez-Arce, I. (Irene), Almagro, G. (Goizeder), Moleres, J. (Javier), Euba, B. (Begoña), Caballero, L. (Lucía), Martí, S. (Sara), Ramos-Vivas, J. (Jose), Leigh-Bartholomew, T. (Toby), Morales-Urteaga, X. (Xabier), Ortiz-de-Solorzano, C. (Carlos), Yuste, J.E. (José Enrique), Bengoechea, J.A. (José A.), Conde-Alvarez, R. (Raquel), Garmendia, J. (Junkal)
Format: info:eu-repo/semantics/article
Language:eng
Published: Nature 2023
Subjects:
Notypeable haemophilus influenzae (NTHi)
Chronic obstructive pulmonary disease (COPD)
Asthma neutrophilic airway inflammation
Online Access:https://hdl.handle.net/10171/65543

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