Comprehensive Analysis of SWI/SNF Inactivation in Lung Adenocarcinoma Cell Models

Comprehensive Analysis of SWI/SNF Inactivation in Lung Adenocarcinoma Cell Models

Mammalian SWI/SNF (SWitch/Sucrose Non-Fermentable) complexes are ATP-dependent chromatin remodelers whose subunits have emerged among the most frequently mutated genes in cancer. Studying SWI/SNF function in cancer cell line models has unveiled vulnerabilities in SWI/SNF-mutant tumors that can le...

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Main Authors: Peinado, P. (Paola), Andrades, A. (Alvaro), Cuadros, M. (Marta), Rodriguez, M.I. (Maria Isabel), Coira, I.F. (Isabel F.), Garcia, D.J. (Daniel J.), Álvarez-Perez, J.C. (Juan Carlos), Baliñas-Gavira, C. (Carlos), Arenas, A.M. (Alberto M.), Patiño-Mercau, J.R. (Juan Rodrigo), Sanjuan-Hidalgo, J. (Juan), Romero, O.A. (Octavio A.), Montuenga-Badia, L.M. (Luis M.), Carretero, J. (Julian), Sanchez-Cespedes, M. (Montserrat), Medina, P.P. (Pedro P.)
Format: info:eu-repo/semantics/article
Language:eng
Published: 2023
Subjects:
SWI/SNF complex
Lung cancer
Lung adenocarcinoma
Epigenetics
Cell models
Multi-omics
Online Access:https://hdl.handle.net/10171/65775

Internet

https://hdl.handle.net/10171/65775

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