Application of ultrasound scores (subjective assessment, simple rules risk assessment, ADNEX model, O-RADS) to adnexal masses of difficult classification
Featured Application Ultrasound scores should consider that some frequent masses such as fibromas, cystoadenofibromas, some mucinous cystadenomas and Brenner tumors may present some characteristics that induce confusion with malignant lesions. Some malignant lesions are not always identified as mali...
| Main Authors: | , , , , , , , , |
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| Format: | info:eu-repo/semantics/article |
| Language: | English |
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2023
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| Online Access: | https://hdl.handle.net/10171/67807 |
| _version_ | 1793399937465057280 |
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| author | Pelayo, M. (Mar) Sancho-Sauco, J. (Javier) Sanchez-Zurdo, J. (Javier) Pérez-Mies, B. (Belen) Abarca-Martinez, L. (Leopoldo) Cancelo-Hidalgo, M.J. (Maria Jesus) Sainz-Bueno, J.A. (Jose Antonio) Alcazar, J.L. (Juan Luis) Pelayo-Delgado, I. (Irene) |
| author_facet | Pelayo, M. (Mar) Sancho-Sauco, J. (Javier) Sanchez-Zurdo, J. (Javier) Pérez-Mies, B. (Belen) Abarca-Martinez, L. (Leopoldo) Cancelo-Hidalgo, M.J. (Maria Jesus) Sainz-Bueno, J.A. (Jose Antonio) Alcazar, J.L. (Juan Luis) Pelayo-Delgado, I. (Irene) |
| author_sort | Pelayo, M. (Mar) |
| collection | DSpace |
| description | Featured Application Ultrasound scores should consider that some frequent masses such as fibromas, cystoadenofibromas, some mucinous cystadenomas and Brenner tumors may present some characteristics that induce confusion with malignant lesions. Some malignant lesions are not always identified as malignant.Abstract Background: Ultrasound features help to differentiate benign from malignant masses, and some of them are included in the ultrasound (US) scores. The main aim of this work is to describe the ultrasound features of certain adnexal masses of difficult classification and to analyse them according to the most frequently used US scores. Methods: Retrospective studies of adnexal lesions are difficult to classify by US scores in women undergoing surgery. Ultrasound characteristics were analysed, and masses were classified according to the Subjective Assessment of the ultrasonographer (SA) and other US scores (IOTA Simple Rules Risk Assessment-SRRA, ADNEX model with and without CA125 and O-RADS). Results: A total of 133 adnexal masses were studied (benign: 66.2%, n:88; malignant: 33.8%, n:45) in a sample of women with mean age 56.5 & PLUSMN; 7.8 years. Malignant lesions were identified by SA in all cases. Borderline ovarian tumors (n:13) were not always detected by some US scores (SRRA: 76.9%, ADNEX model without and with CA125: 76.9% and 84.6%) nor were serous carcinoma (n:19) (SRRA: 89.5%), clear cell carcinoma (n:9) (SRRA: 66.7%) or endometrioid carcinoma (n:4) (ADNEX model without CA125: 75.0%). While most teratomas and serous cystadenomas have been correctly differentiated, other benign lesions were misclassified because of the presence of solid areas or papillae. Fibromas (n:13) were better identified by SA (23.1% malignancy), but worse with the other US scores (SRRA: 69.2%, ADNEX model without and with CA125: 84.6% and 69.2%, O-RADS: 53.8%). Cystoadenofibromas (n:10) were difficult to distinguish from malignant masses via all scores except SRRA (SA: 70.0%, SRRA: 20.0%, ADNEX model without and with CA125: 60.0% and 50.0%, O-RADS: 90.0%). Mucinous cystadenomas (n:12) were misdiagnosed as malignant in more than 15% of the cases in all US scores (SA: 33.3%, SRRA: 16.7%, ADNEX model without and with CA125: 16.7% and 16.7%, O-RADS:41.7%). Brenner tumors are also difficult to classify using all scores. Conclusion: Some malignant masses (borderline ovarian tumors, serous carcinoma, clear cell carcinoma, endometrioid carcinomas) are not always detected by US scores. Fibromas, cystoadenofibromas, some mucinous cystadenomas and Brenner tumors may present solid components/papillae that may induce confusion with malignant lesions. Most teratomas and serous cystadenomas are usually correctly classified. |
| format | info:eu-repo/semantics/article |
| id | oai:dadun.unav.edu:10171-67807 |
| institution | Universidad de Navarra |
| language | English |
| publishDate | 2023 |
| record_format | dspace |
| spelling | oai:dadun.unav.edu:10171-678072023-11-27T06:06:15Z Application of ultrasound scores (subjective assessment, simple rules risk assessment, ADNEX model, O-RADS) to adnexal masses of difficult classification Pelayo, M. (Mar) Sancho-Sauco, J. (Javier) Sanchez-Zurdo, J. (Javier) Pérez-Mies, B. (Belen) Abarca-Martinez, L. (Leopoldo) Cancelo-Hidalgo, M.J. (Maria Jesus) Sainz-Bueno, J.A. (Jose Antonio) Alcazar, J.L. (Juan Luis) Pelayo-Delgado, I. (Irene) Área de Medicina Clínica y Epidemiología Transvaginal ultrasound Adnexal masses IOTA simple rules risk assessment O-RADS ADNEX model CA125 Subjective assessment Mature cystic teratoma Serous cystadenoma Mucinous cystadenoma Brenner tumour Cystadenofibroma Fibroma Borderline carcinoma Serous ovarian carcinoma Clear cell carcinoma Endometriod carcinoma Featured Application Ultrasound scores should consider that some frequent masses such as fibromas, cystoadenofibromas, some mucinous cystadenomas and Brenner tumors may present some characteristics that induce confusion with malignant lesions. Some malignant lesions are not always identified as malignant.Abstract Background: Ultrasound features help to differentiate benign from malignant masses, and some of them are included in the ultrasound (US) scores. The main aim of this work is to describe the ultrasound features of certain adnexal masses of difficult classification and to analyse them according to the most frequently used US scores. Methods: Retrospective studies of adnexal lesions are difficult to classify by US scores in women undergoing surgery. Ultrasound characteristics were analysed, and masses were classified according to the Subjective Assessment of the ultrasonographer (SA) and other US scores (IOTA Simple Rules Risk Assessment-SRRA, ADNEX model with and without CA125 and O-RADS). Results: A total of 133 adnexal masses were studied (benign: 66.2%, n:88; malignant: 33.8%, n:45) in a sample of women with mean age 56.5 & PLUSMN; 7.8 years. Malignant lesions were identified by SA in all cases. Borderline ovarian tumors (n:13) were not always detected by some US scores (SRRA: 76.9%, ADNEX model without and with CA125: 76.9% and 84.6%) nor were serous carcinoma (n:19) (SRRA: 89.5%), clear cell carcinoma (n:9) (SRRA: 66.7%) or endometrioid carcinoma (n:4) (ADNEX model without CA125: 75.0%). While most teratomas and serous cystadenomas have been correctly differentiated, other benign lesions were misclassified because of the presence of solid areas or papillae. Fibromas (n:13) were better identified by SA (23.1% malignancy), but worse with the other US scores (SRRA: 69.2%, ADNEX model without and with CA125: 84.6% and 69.2%, O-RADS: 53.8%). Cystoadenofibromas (n:10) were difficult to distinguish from malignant masses via all scores except SRRA (SA: 70.0%, SRRA: 20.0%, ADNEX model without and with CA125: 60.0% and 50.0%, O-RADS: 90.0%). Mucinous cystadenomas (n:12) were misdiagnosed as malignant in more than 15% of the cases in all US scores (SA: 33.3%, SRRA: 16.7%, ADNEX model without and with CA125: 16.7% and 16.7%, O-RADS:41.7%). Brenner tumors are also difficult to classify using all scores. Conclusion: Some malignant masses (borderline ovarian tumors, serous carcinoma, clear cell carcinoma, endometrioid carcinomas) are not always detected by US scores. Fibromas, cystoadenofibromas, some mucinous cystadenomas and Brenner tumors may present solid components/papillae that may induce confusion with malignant lesions. Most teratomas and serous cystadenomas are usually correctly classified. 2023-11-06T13:34:31Z 2023-11-06T13:34:31Z 2023 info:eu-repo/semantics/article https://hdl.handle.net/10171/67807 en info:eu-repo/semantics/openAccess application/pdf |
| spellingShingle | Área de Medicina Clínica y Epidemiología Transvaginal ultrasound Adnexal masses IOTA simple rules risk assessment O-RADS ADNEX model CA125 Subjective assessment Mature cystic teratoma Serous cystadenoma Mucinous cystadenoma Brenner tumour Cystadenofibroma Fibroma Borderline carcinoma Serous ovarian carcinoma Clear cell carcinoma Endometriod carcinoma Pelayo, M. (Mar) Sancho-Sauco, J. (Javier) Sanchez-Zurdo, J. (Javier) Pérez-Mies, B. (Belen) Abarca-Martinez, L. (Leopoldo) Cancelo-Hidalgo, M.J. (Maria Jesus) Sainz-Bueno, J.A. (Jose Antonio) Alcazar, J.L. (Juan Luis) Pelayo-Delgado, I. (Irene) Application of ultrasound scores (subjective assessment, simple rules risk assessment, ADNEX model, O-RADS) to adnexal masses of difficult classification |
| title | Application of ultrasound scores (subjective assessment, simple rules risk assessment, ADNEX model, O-RADS) to adnexal masses of difficult classification |
| title_full | Application of ultrasound scores (subjective assessment, simple rules risk assessment, ADNEX model, O-RADS) to adnexal masses of difficult classification |
| title_fullStr | Application of ultrasound scores (subjective assessment, simple rules risk assessment, ADNEX model, O-RADS) to adnexal masses of difficult classification |
| title_full_unstemmed | Application of ultrasound scores (subjective assessment, simple rules risk assessment, ADNEX model, O-RADS) to adnexal masses of difficult classification |
| title_short | Application of ultrasound scores (subjective assessment, simple rules risk assessment, ADNEX model, O-RADS) to adnexal masses of difficult classification |
| title_sort | application of ultrasound scores (subjective assessment, simple rules risk assessment, adnex model, o-rads) to adnexal masses of difficult classification |
| topic | Área de Medicina Clínica y Epidemiología Transvaginal ultrasound Adnexal masses IOTA simple rules risk assessment O-RADS ADNEX model CA125 Subjective assessment Mature cystic teratoma Serous cystadenoma Mucinous cystadenoma Brenner tumour Cystadenofibroma Fibroma Borderline carcinoma Serous ovarian carcinoma Clear cell carcinoma Endometriod carcinoma |
| url | https://hdl.handle.net/10171/67807 |
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