Regulation and role of the PP2A-B56 holoenzyme family in cancer

Protein phosphatase 2A (PP2A) inactivation is common in cancer, leading to sustained activation of pro-survival and growth-promoting pathways. PP2A consists of a scaffolding A-subunit, a catalytic C-subunit, and a regulatory B-subunit. The functional complexity of PP2A holoenzymes arises mainly thro...

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Bibliographic Details
Main Authors: Peris-Martínez, I. (Irene), Romero-Murillo, S. (Silvia), Vicente-Vázquez, C. (Carmen), Narla, G., Odero-de Dios, M. (María Dolores)
Format: info:eu-repo/semantics/review
Language:English
Published: 2023
Subjects:
Online Access:https://hdl.handle.net/10171/67832