Studying the role of BCL2 and MYC in the pathogenesis of diffuse large B cell lymphoma

Studying the role of BCL2 and MYC in the pathogenesis of diffuse large B cell lymphoma

Approximately 30% of patients with diffuse large B-cell lymphoma (DLBCL) co-express BCL2 and MYC, known as double-expressor lymphomas (DEL). These lymphomas associate with poorer prognosis and response to standard-of-care R-CHOP, and a preferred therapeutic alternative has not been identified yet...

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Bibliographic Details
Main Authors: Sánchez, J. (Javier), Martinez-Climent, J.A. (José Ángel), Roa, S. (Sergio)
Format: info:eu-repo/semantics/doctoralThesis
Language:eng
Published: Universidad de Navarra 2023
Subjects:
Materias Investigacion::Ciencias de la Salud::Genética
Diffuse large B cell lymphoma
BCL2
MYC
B-Cell lymphomagenesis
Linfoma difuso de células B
Online Access:https://hdl.handle.net/10171/68058

Internet

https://hdl.handle.net/10171/68058

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