Practice-oriented solutions integrating intraoperative electron irradiation and personalized proton therapy for recurrent or unresectable cancers: Proof of concept and potential for dual FLASH effect

Background: Oligo-recurrent disease has a consolidated evidence of long-term surviving patients due to the use of intense local cancer therapy. The latter combines real-time surgical exploration/resection with high-energy electron beam single dose of irradiation. This results in a very precise radia...

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Main Authors: Calvo, F.A. (Felipe A.), Ayestaran, A. (Adriana), Serrano-Andreu, J. (Javier), Cambeiro, M. (Mauricio), Palma, J. (Jacobo), Meiriño, R. (Rosa), Morcillo, M.A. (Miguel Ángel), Lapuente, F. (Fernando), Chiva, L. (Luis), Aguilar, B. (Borja), Azcona, J.D. (Juan Diego), Pedrero, D. (Diego), Pascau, J. (Javier), Delgado, J.M. (José Miguel), Aristu-Mendioroz, J.J. (José Javier), Alonso, A. (Alberto), Prezado, Y. (Yolanda)
Format: info:eu-repo/semantics/article
Language:eng
Published: Frontiers 2024
Subjects:
Online Access:https://hdl.handle.net/10171/68824