Divergent Strategy in Marine Tetracyclic Meroterpenoids Synthesis

The divergent total synthesis strategy can be successfully applied to the preparation of families of natural products using a common late-stage pluripotent intermediate. This approach is a powerful tool in organic synthesis as it offers opportunities for the efficient preparation of structurally rel...

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Bibliografiske detaljer
Main Authors: Rosales Martínez, Antonio, Rodríguez García, Ignacio Manuel, López Martínez, Josefa Leticia
Format: info:eu-repo/semantics/article
Sprog:English
Udgivet: MDPI 2021
Fag:
Online adgang:http://hdl.handle.net/10835/11927
https://doi.org/10.3390/md19050273
Beskrivelse
Summary:The divergent total synthesis strategy can be successfully applied to the preparation of families of natural products using a common late-stage pluripotent intermediate. This approach is a powerful tool in organic synthesis as it offers opportunities for the efficient preparation of structurally related compounds. This article reviews the synthesis of the marine natural product aureol, as well as its use as a common intermediate in the divergent synthesis of other marine natural and non-natural tetracyclic meroterpenoids