Quadruplex Ligands in Cancer Therapy

Nucleic acids can adopt alternative secondary conformations including four-stranded structures known as quadruplexes. To date, quadruplexes have been demonstrated to exist both in human chromatin DNA and RNA. In particular, quadruplexes are found in guanine-rich sequences constituting G-quadruplexes...

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Bibliographic Details
Main Authors: Sánchez Martín, Victoria, Soriano Rodríguez, Miguel, García Salcedo, José Antonio
Format: info:eu-repo/semantics/article
Language:English
Published: MDPI 2021
Subjects:
Online Access:http://hdl.handle.net/10835/11929
https://doi.org/10.3390/cancers13133156