pH-Driven Polymorphic Behaviour of the Third PDZ Domain of PSD95: The Role of Electrostatic Interactions

pH-Driven Polymorphic Behaviour of the Third PDZ Domain of PSD95: The Role of Electrostatic Interactions

The PDZ domains are modular domains that recognise short linear C-terminal sequences in proteins that organise the formation of complex multi-component assemblies. We have crystallised the third PDZ domain of the neuronal postsynaptic density-95 protein (PSD95-PDZ3) at mildly acidic pH conditions an...

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Bibliographic Details
Main Authors: Salinas García, María Del Carmen, Plaza Garrido, Marina, Gavira, Jose A., Murciano‐Calles, Javier, Andújar Sánchez, Montserrat, Ortiz Salmerón, Emilia, Martinez, Jose C., Cámara Artigas, Ana María
Format: info:eu-repo/semantics/article
Language:English
Published: MDPI 2023
Subjects:
PDZ domain
X‐ray structures
conformational changes
polymorphs
electrostatic interactions
Online Access:http://hdl.handle.net/10835/14165

Internet

http://hdl.handle.net/10835/14165

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