Effect of hypoxia on caveolin-1 expression, caveolae structure and insulin signaling

Obesity courses with the hypertrophy and hyperplasia of adipose tissue, which has been related to the development of hypoxia and, as consequence, insulin resistance. In this sense, insulin receptor is enriched in a specialized invagination of the plasma membrane named caveolae. Caveolin-1 (Cav-1) is...

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Detalles Bibliográficos
Main Authors: Varela-Guruceaga, M. (Maider), Miguel-Vázquez, C. (Carlos) de, Milagro-Yoldi, F.I. (Fermín Ignacio)
Formato: info:eu-repo/semantics/doctoralThesis
Idioma:eng
Publicado: 2019
Subjects:
Acceso en liña:https://hdl.handle.net/10171/56365