Evaluation of skin permeation and retention of topical dapsone in murine cutaneous leishmaniasis lesions

The oral administration of dapsone (DAP) for the treatment of cutaneous leishmaniasis (CL) is effective, although serious hematological side effects limit its use. In this study, we evaluated this drug for the topical treatment of CL. As efficacy depends on potency and skin penetration, we first det...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Espuelas, S. (Socorro), Irache, J.M. (Juan Manuel), Sanmartin-Grijalba, C. (Carmen), Gonzalez-Peñas, E. (Elena), Navarro-Blasco, I. (Iñigo), Schwartz, J. (Juana), Calvo-Bacaicoa, A. (Alba), Moreno-Amatria, E. (Esther)
التنسيق: info:eu-repo/semantics/article
اللغة:English
منشور في: 2019
الموضوعات:
الوصول للمادة أونلاين:https://hdl.handle.net/10171/58480