Evaluation of skin permeation and retention of topical dapsone in murine cutaneous leishmaniasis lesions

Evaluation of skin permeation and retention of topical dapsone in murine cutaneous leishmaniasis lesions

The oral administration of dapsone (DAP) for the treatment of cutaneous leishmaniasis (CL) is effective, although serious hematological side effects limit its use. In this study, we evaluated this drug for the topical treatment of CL. As efficacy depends on potency and skin penetration, we first det...

Description complète

Détails bibliographiques
Auteurs principaux: Espuelas, S. (Socorro), Irache, J.M. (Juan Manuel), Sanmartin-Grijalba, C. (Carmen), Gonzalez-Peñas, E. (Elena), Navarro-Blasco, I. (Iñigo), Schwartz, J. (Juana), Calvo-Bacaicoa, A. (Alba), Moreno-Amatria, E. (Esther)
Format: info:eu-repo/semantics/article
Langue:English
Publié: 2019
Sujets:
Dapsone
Topical treatment
Cutaneous leishmaniasis
Pluronic lecithin emulgel
Iron
Accès en ligne:https://hdl.handle.net/10171/58480

Internet

https://hdl.handle.net/10171/58480

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