A permeability-increasing drug synergizes with bacterial efux pump inhibitors and restores susceptibility to antibiotics in multi-drug resistant Pseudomonas aeruginosa strains

Resistance to antibiotics poses a major global threat according to the World Health Organization. Restoring the activity of existing drugs is an attractive alternative to address this challenge. One of the most efficient mechanisms of bacterial resistance involves the expression of efflux pump syste...

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Main Authors: Raquel, Shahrour, H. (Hawraa), Pitts, B. (Betsey), Stewart, P.S. (Philip S.), Sánchez-Gómez, S. (Susana), Martinez-de-Tejada, G. (Guillermo)
格式: info:eu-repo/semantics/article
语言:eng
出版: Springer Science and Business Media LLC 2021
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在线阅读:https://hdl.handle.net/10171/62141