Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk
Background: The effect of dietary fat intake on the metabolic syndrome (MetS) and in turn on cardiovascular disease (CVD) remains unclear in individuals at high CVD risk. Objective: To assess the association between fat intake and MetS components in an adult Mediterranean population at high CVD risk...
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| Format: | info:eu-repo/semantics/article |
| Language: | eng |
| Published: |
MDPI AG
2021
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10171/62053 |
| _version_ | 1793400063528009728 |
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| author | Julibert, A. (Alicia) Bibiloni, M.M. (Maria del Mar) Bouzas, C. (Cristina) Martinez-Gonzalez, M.A. (Miguel Ángel) Salas-Salvado, J. (Jordi) Corella, D. (Dolores) Zomeño, M.D. (María Dolores) Romaguera, D. (Dora) Vioque, J. (Jesús) Alonso-Gomez, A. (Ángel) Wärnberg, J. (Julia) Martinez, A. (Alfredo) Serra-Majem, L. (Luis) Estruch, R. (Ramón) Tinahones, F.J. (Francisco J.) Lapetra, J. (José) Pinto, X. (Xavier) López-Miranda, J. (José) García-Molina, L. (Laura) Gaforio, J.J. (José Juan) Matía-Martín, P. (Pilar) Daimiel, L. (Lidia) Martín-Sánchez, V. (Vicente) Vidal, J. (Josep) Vázquez, C. (Clotilde) Ros, E. (Emilio) Toledo, E. (Estefanía) Becerra-Tomas, N. (Nerea) Portoles, O. (Olga) Perez-Vega, K.A. (Karla Alejandra) Fiol, M. (Miquel) Torres-Collado, L. (Laura) Tojal-Sierra, L. (Lucas) Carabaño-Moral, R. (Rosa) Abete, I. (Itziar) Sanchez-Villegas, A. (Almudena) Casas, R. (Rosa) Bernal-López, M.R. (María Rosa) Santos-Lozano, J.M. (José M.) Galera, A. (Ana) Ugarriza, L. (Lucía) Ruiz-Canela, M. (Miguel) Babio, N. (Nancy) Coltell, O. (Oscar) Schröder, H. (Helmut) Konieczna, J. (Jadwiga) Orozco-Beltrán, D. (Domingo) Sorto-Sánchez, C. (Carolina) Eguaras, S. (Sonia) Barrubés, L. (Laura) Fito, M. (Montserrat) Tur, J.A. (Josep A.) PREDIMED-PLUS Investigators |
| author_facet | Julibert, A. (Alicia) Bibiloni, M.M. (Maria del Mar) Bouzas, C. (Cristina) Martinez-Gonzalez, M.A. (Miguel Ángel) Salas-Salvado, J. (Jordi) Corella, D. (Dolores) Zomeño, M.D. (María Dolores) Romaguera, D. (Dora) Vioque, J. (Jesús) Alonso-Gomez, A. (Ángel) Wärnberg, J. (Julia) Martinez, A. (Alfredo) Serra-Majem, L. (Luis) Estruch, R. (Ramón) Tinahones, F.J. (Francisco J.) Lapetra, J. (José) Pinto, X. (Xavier) López-Miranda, J. (José) García-Molina, L. (Laura) Gaforio, J.J. (José Juan) Matía-Martín, P. (Pilar) Daimiel, L. (Lidia) Martín-Sánchez, V. (Vicente) Vidal, J. (Josep) Vázquez, C. (Clotilde) Ros, E. (Emilio) Toledo, E. (Estefanía) Becerra-Tomas, N. (Nerea) Portoles, O. (Olga) Perez-Vega, K.A. (Karla Alejandra) Fiol, M. (Miquel) Torres-Collado, L. (Laura) Tojal-Sierra, L. (Lucas) Carabaño-Moral, R. (Rosa) Abete, I. (Itziar) Sanchez-Villegas, A. (Almudena) Casas, R. (Rosa) Bernal-López, M.R. (María Rosa) Santos-Lozano, J.M. (José M.) Galera, A. (Ana) Ugarriza, L. (Lucía) Ruiz-Canela, M. (Miguel) Babio, N. (Nancy) Coltell, O. (Oscar) Schröder, H. (Helmut) Konieczna, J. (Jadwiga) Orozco-Beltrán, D. (Domingo) Sorto-Sánchez, C. (Carolina) Eguaras, S. (Sonia) Barrubés, L. (Laura) Fito, M. (Montserrat) Tur, J.A. (Josep A.) PREDIMED-PLUS Investigators |
| author_sort | Julibert, A. (Alicia) |
| collection | DSpace |
| description | Background: The effect of dietary fat intake on the metabolic syndrome (MetS) and in turn on cardiovascular disease (CVD) remains unclear in individuals at high CVD risk. Objective: To assess the association between fat intake and MetS components in an adult Mediterranean population at high CVD risk. Design: Baseline assessment of nutritional adequacy in participants (n = 6560, men and women, 55-75 years old, with overweight/obesity and MetS) in the PREvención con DIeta MEDiterránea (PREDIMED)-Plus randomized trial. Methods: Assessment of fat intake (total fat, monounsatured fatty acids: MUFA, polyunsaturated fatty acids: PUFA, saturated fatty acids: SFA, trans-fatty acids: trans-FA, linoleic acid, α-linolenic acid, and ω-3 FA) using a validated food frequency questionnaire, and diet quality using 17-item Mediterranean dietary questionnaire and fat quality index (FQI). Results: Participants in the highest quintile of total dietary fat intake showed lower intake of energy, carbohydrates, protein and fiber, but higher intake of PUFA, MUFA, SFA, TFA, LA, ALA and ω-3 FA. Differences in MetS components were found according to fat intake. Odds (5th vs. 1st quintile): hyperglycemia: 1.3-1.6 times higher for total fat, MUFA, SFA and ω-3 FA intake; low high-density lipoprotein cholesterol (HDL-c): 1.2 higher for LA; hypertriglyceridemia: 0.7 lower for SFA and ω-3 FA intake. Conclusions: Dietary fats played different role on MetS components of high CVD risk patients. Dietary fat intake was associated with higher risk of hyperglycemia. |
| format | info:eu-repo/semantics/article |
| id | oai:dadun.unav.edu:10171-62053 |
| institution | Universidad de Navarra |
| language | eng |
| publishDate | 2021 |
| publisher | MDPI AG |
| record_format | dspace |
| spelling | oai:dadun.unav.edu:10171-620532023-05-29T12:38:51Z Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk Julibert, A. (Alicia) Bibiloni, M.M. (Maria del Mar) Bouzas, C. (Cristina) Martinez-Gonzalez, M.A. (Miguel Ángel) Salas-Salvado, J. (Jordi) Corella, D. (Dolores) Zomeño, M.D. (María Dolores) Romaguera, D. (Dora) Vioque, J. (Jesús) Alonso-Gomez, A. (Ángel) Wärnberg, J. (Julia) Martinez, A. (Alfredo) Serra-Majem, L. (Luis) Estruch, R. (Ramón) Tinahones, F.J. (Francisco J.) Lapetra, J. (José) Pinto, X. (Xavier) López-Miranda, J. (José) García-Molina, L. (Laura) Gaforio, J.J. (José Juan) Matía-Martín, P. (Pilar) Daimiel, L. (Lidia) Martín-Sánchez, V. (Vicente) Vidal, J. (Josep) Vázquez, C. (Clotilde) Ros, E. (Emilio) Toledo, E. (Estefanía) Becerra-Tomas, N. (Nerea) Portoles, O. (Olga) Perez-Vega, K.A. (Karla Alejandra) Fiol, M. (Miquel) Torres-Collado, L. (Laura) Tojal-Sierra, L. (Lucas) Carabaño-Moral, R. (Rosa) Abete, I. (Itziar) Sanchez-Villegas, A. (Almudena) Casas, R. (Rosa) Bernal-López, M.R. (María Rosa) Santos-Lozano, J.M. (José M.) Galera, A. (Ana) Ugarriza, L. (Lucía) Ruiz-Canela, M. (Miguel) Babio, N. (Nancy) Coltell, O. (Oscar) Schröder, H. (Helmut) Konieczna, J. (Jadwiga) Orozco-Beltrán, D. (Domingo) Sorto-Sánchez, C. (Carolina) Eguaras, S. (Sonia) Barrubés, L. (Laura) Fito, M. (Montserrat) Tur, J.A. (Josep A.) PREDIMED-PLUS Investigators Materias Investigacion::Ciencias de la Salud::Medicina preventiva Mediterranean diet Cardiovascular disease risk Dietary fat Fat intake Fatty acids Background: The effect of dietary fat intake on the metabolic syndrome (MetS) and in turn on cardiovascular disease (CVD) remains unclear in individuals at high CVD risk. Objective: To assess the association between fat intake and MetS components in an adult Mediterranean population at high CVD risk. Design: Baseline assessment of nutritional adequacy in participants (n = 6560, men and women, 55-75 years old, with overweight/obesity and MetS) in the PREvención con DIeta MEDiterránea (PREDIMED)-Plus randomized trial. Methods: Assessment of fat intake (total fat, monounsatured fatty acids: MUFA, polyunsaturated fatty acids: PUFA, saturated fatty acids: SFA, trans-fatty acids: trans-FA, linoleic acid, α-linolenic acid, and ω-3 FA) using a validated food frequency questionnaire, and diet quality using 17-item Mediterranean dietary questionnaire and fat quality index (FQI). Results: Participants in the highest quintile of total dietary fat intake showed lower intake of energy, carbohydrates, protein and fiber, but higher intake of PUFA, MUFA, SFA, TFA, LA, ALA and ω-3 FA. Differences in MetS components were found according to fat intake. Odds (5th vs. 1st quintile): hyperglycemia: 1.3-1.6 times higher for total fat, MUFA, SFA and ω-3 FA intake; low high-density lipoprotein cholesterol (HDL-c): 1.2 higher for LA; hypertriglyceridemia: 0.7 lower for SFA and ω-3 FA intake. Conclusions: Dietary fats played different role on MetS components of high CVD risk patients. Dietary fat intake was associated with higher risk of hyperglycemia. 2021-09-23T09:36:18Z 2021-09-23T09:36:18Z 2019 info:eu-repo/semantics/article https://hdl.handle.net/10171/62053 eng info:eu-repo/grantAgreement/EC/FP7/340918/EU info:eu-repo/semantics/openAccess application/pdf MDPI AG |
| spellingShingle | Materias Investigacion::Ciencias de la Salud::Medicina preventiva Mediterranean diet Cardiovascular disease risk Dietary fat Fat intake Fatty acids Julibert, A. (Alicia) Bibiloni, M.M. (Maria del Mar) Bouzas, C. (Cristina) Martinez-Gonzalez, M.A. (Miguel Ángel) Salas-Salvado, J. (Jordi) Corella, D. (Dolores) Zomeño, M.D. (María Dolores) Romaguera, D. (Dora) Vioque, J. (Jesús) Alonso-Gomez, A. (Ángel) Wärnberg, J. (Julia) Martinez, A. (Alfredo) Serra-Majem, L. (Luis) Estruch, R. (Ramón) Tinahones, F.J. (Francisco J.) Lapetra, J. (José) Pinto, X. (Xavier) López-Miranda, J. (José) García-Molina, L. (Laura) Gaforio, J.J. (José Juan) Matía-Martín, P. (Pilar) Daimiel, L. (Lidia) Martín-Sánchez, V. (Vicente) Vidal, J. (Josep) Vázquez, C. (Clotilde) Ros, E. (Emilio) Toledo, E. (Estefanía) Becerra-Tomas, N. (Nerea) Portoles, O. (Olga) Perez-Vega, K.A. (Karla Alejandra) Fiol, M. (Miquel) Torres-Collado, L. (Laura) Tojal-Sierra, L. (Lucas) Carabaño-Moral, R. (Rosa) Abete, I. (Itziar) Sanchez-Villegas, A. (Almudena) Casas, R. (Rosa) Bernal-López, M.R. (María Rosa) Santos-Lozano, J.M. (José M.) Galera, A. (Ana) Ugarriza, L. (Lucía) Ruiz-Canela, M. (Miguel) Babio, N. (Nancy) Coltell, O. (Oscar) Schröder, H. (Helmut) Konieczna, J. (Jadwiga) Orozco-Beltrán, D. (Domingo) Sorto-Sánchez, C. (Carolina) Eguaras, S. (Sonia) Barrubés, L. (Laura) Fito, M. (Montserrat) Tur, J.A. (Josep A.) PREDIMED-PLUS Investigators Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk |
| title | Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk |
| title_full | Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk |
| title_fullStr | Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk |
| title_full_unstemmed | Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk |
| title_short | Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk |
| title_sort | total and subtypes of dietary fat intake and its association with components of the metabolic syndrome in a mediterranean population at high cardiovascular risk |
| topic | Materias Investigacion::Ciencias de la Salud::Medicina preventiva Mediterranean diet Cardiovascular disease risk Dietary fat Fat intake Fatty acids |
| url | https://hdl.handle.net/10171/62053 |
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