Dual targeting of histone methyltransferase G9a and DNMT1 for the treatment of experimental hepatocellular carcinoma
Las modificaciones epigenéticas, como la metilación del ADN e histonas, cooperan funcionalmente para fomentar el crecimiento tumoral, incluido el carcinoma hepatocelular (HCC). La inhibición farmacológica de estos mecanismos puede abrir nuevas vías terapéuticas. El objetivo del trabajo desarrollado...
Main Authors: | Bárcena-Varela, M. (Marina), Avila, M.A. (Matías Antonio), García-Fernández-de-Barrena, M. (Maite) |
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Format: | info:eu-repo/semantics/doctoralThesis |
Language: | eng |
Published: |
2019
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Subjects: | |
Online Access: | https://hdl.handle.net/10171/56392 |
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